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<span style="font-size: initial; text-align: initial; line-height: initial;"><font face="Calibri, Slate Pro, sans-serif">Dear Martin</font></span></div>
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<span style="font-size: initial; text-align: initial; line-height: initial;"><font face="Calibri, Slate Pro, sans-serif">Thanks for that clarification. Fortunately lowering of CO from a fire is relatively easy and from an IAQ point of view is easy to remove
by using a chimney or ventilation. </font></span></div>
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<span style="font-size: initial; text-align: initial; line-height: initial;"><font face="Calibri, Slate Pro, sans-serif">You used smoking as a comparison which is useful. Smoke from a cigarette has a massive CO level because it is smouldering, not burning.
I was wondering if there is a 'narcotic' effect of hypoxia what attracts people to the habit. </font></span></div>
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<span style="font-size: initial; text-align: initial; line-height: initial;"><font face="Calibri, Slate Pro, sans-serif">Regards </font></span></div>
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<span style="font-size: initial; text-align: initial; line-height: initial;"><font face="Calibri, Slate Pro, sans-serif">Crispin
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<div style="word-wrap:break-word"><span style="font-size:12px">Hi,</span>
<div><span style="font-size:12px">I must correct myself about anemia !</span></div>
<div><span style="font-size:12px">We should not call the effect of CO anaemia, because that is per definition lack of erythrocyths, that means no erys at all, or at least a too small number of them.</span></div>
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<div><span style="font-size:12px">but CO makes a competitive blocking of oxygen, while all the red blood-bodies are still in circulation.</span></div>
<div><span style="font-size:12px">The effect of severe anemia/erythropenia as well as the effect of CO is called _hypoxia</span><span style="font-size:14px">_</span><span style="font-size:12px">, the shortage of oxygen in the tissue.</span></div>
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<div><span style="font-size:12px">- Smokers built an extra portion of erys to compensate the number of erys which are for the time blocked by CO until CO is no more in the inspiration-air, and so disappears very very slowly.</span></div>
<div><span style="font-size:12px"> Yes, Crispin, CO is itself part of metabolism even it is in normal air, but that is all a lower range. </span></div>
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<div><span style="font-size:12px">- By the way: Sharply seen means anaemia normally only an erythropenia, not a </span><span style="font-size:12px">totally absence of erythrocyts, -as in the sense of the word.-</span></div>
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<div><span style="font-size:12px">After the hemoglobin is released from CO, the erythrocyt transports again O2</span></div>
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<div><span style="font-size:12px">Regards</span></div>
<div><span style="font-size:12px">Martin</span></div>
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<div><span style="font-size:12px">Hi,</span></div>
<div><span style="font-size:12px">The website I had cited <a href="http://de.wikipedia.org/wiki/Kohlenstoffmonoxid">http://de.wikipedia.org/wiki/Kohlenstoffmonoxid</a> </span></div>
<div><span style="font-size:12px">is worth to notice. There is information that </span></div>
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<div><span style="font-size:14px">CO is far more different than only making anemia as shortage of erythrocytes.</span></div>
<div><span style="background-color:rgb(255,255,255); color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px">e.g.:</span></div>
<div><span style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)">"Sowohl Stickstoff- als auch Kohlenstoffmonoxid können als extrem niedermolekulare, wasserlösliche Gase sehr schnell und relativ
unbehindert </span><a href="http://de.wikipedia.org/wiki/Biomembran" title="Biomembran" style="text-decoration:none; color:rgb(11,0,128); background-color:rgb(255,255,255); font-family:sans-serif; font-size:14px; line-height:22px">Biomembranen</a><span style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)"> durchdringen
und dienen deshalb als</span><a href="http://de.wikipedia.org/wiki/Neurotransmitter" title="Neurotransmitter" style="text-decoration:none; color:rgb(11,0,128); background-color:rgb(255,255,255); font-family:sans-serif; font-size:14px; line-height:22px">Neurotransmitter</a><span style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)"> bei
der Übertragung von Informationen aus dem </span><i style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)">primären</i><span style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)"> oder </span><i style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)">sensorischen</i><span style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)"> in
das </span><i style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)">sekundäre</i><span style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)"> oder </span><i style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)">Langzeit</i><a href="http://de.wikipedia.org/wiki/Ged%C3%A4chtnis" title="Gedächtnis" style="text-decoration:none; color:rgb(11,0,128); background-color:rgb(255,255,255); font-family:sans-serif; font-size:14px; line-height:22px">gedächtnis</a><span style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)"> durch
das </span><a href="http://de.wikipedia.org/wiki/Limbisches_System" title="Limbisches System" style="text-decoration:none; color:rgb(11,0,128); background-color:rgb(255,255,255); font-family:sans-serif; font-size:14px; line-height:22px">limbische System</a><span style="color:rgb(37,37,37); font-family:sans-serif; font-size:14px; line-height:22px; background-color:rgb(255,255,255)">.</span><sup id="x_cite_ref-50" class="x_reference" style="line-height:1; color:rgb(37,37,37); font-family:sans-serif; background-color:rgb(255,255,255)"><a href="http://de.wikipedia.org/wiki/Kohlenstoffmonoxid#cite_note-50" style="text-decoration:none; color:rgb(11,0,128)">[50]</a></sup><sup id="x_cite_ref-51" class="x_reference" style="line-height:1; color:rgb(37,37,37); font-family:sans-serif; background-color:rgb(255,255,255)"><a href="http://de.wikipedia.org/wiki/Kohlenstoffmonoxid#cite_note-51" style="text-decoration:none; color:rgb(11,0,128)">[51]</a>"</sup></div>
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<div><span style="font-size:12px">I'll try to translate:</span></div>
<div><span style="font-size:12px">Nitrogen as well as carbonmonoxide can, as low-molecular, water-soluble gasses transit relatively light biomembranes and use to be therefore as neurotransmitters by the sending of information out of the primary or sensory into
the secondary or longtimebrain via the limbic system.</span></div>
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<div><span style="font-size:12px">Regards</span></div>
<div><span style="font-size:12px">Martin</span></div>
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