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</o:shapelayout></xml><![endif]--></head><body lang=EN-CA link=blue vlink=purple><div class=WordSection1><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D;mso-fareast-language:EN-US'>Dear B.C.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Do you think that the children and adults, remembering that the children have 1/3 the exposure time, both reached CO equilibrium by the time they were measured?<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>If so the results indicate that the absorption by children is much faster, but that it may not result in higher levels in the bloodstream.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>If this is the case, it is an important aspect of the toxicology. At some point the CO will equilibrate – I am just wondering if we can assert that it happens in 1/3 the time, children v.s adults, the ultimate level being determined by the available ‘supply’.<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Thanks<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Crispin<o:p></o:p></span></p><p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p><div><h2 style='mso-margin-top-alt:7.5pt;margin-right:0mm;margin-bottom:0mm;margin-left:0mm;margin-bottom:.0001pt'><span style='font-size:14.5pt;font-family:"Georgia","serif";color:black'><a href="http://ehs.sph.berkeley.edu/krsmith/?p=993"><span style='color:#174C6D;text-decoration:none'>Non-invasive measurement of carbon monoxide burden in Guatemalan children and adults following wood-fired temazcal (sauna-bath) use</span></a><o:p></o:p></span></h2><div><p style='line-height:18.0pt'><span style='font-size:10.5pt;font-family:"Georgia","serif";color:black'>Lam, N., Nicas, M., Ruiz-Mercado, I., & Thompson, L., Romero, C., Smith K.R. (2011). Non-invasive measurement of carbon monoxide burden in Guatemalan children and adults following wood-fired temazcal (sauna-bath) use. Journal of Environmental Monitoring.</span><span style='font-size:10.5pt;color:black'>→</span><span style='font-size:10.5pt;font-family:"Georgia","serif";color:black'> Download PDF<o:p></o:p></span></p></div><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:18.0pt'><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";color:black'><a href="http://ehs.sph.berkeley.edu/krsmith/?p=993"><span style='color:#174C6D;text-decoration:none'>http://ehs.sph.berkeley.edu/krsmith/?p=993</span></a><o:p></o:p></span></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:18.0pt'><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";color:black'><o:p> </o:p></span></p><p class=MsoNormal style='mso-margin-top-alt:auto;mso-margin-bottom-alt:auto;line-height:18.0pt'><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";color:black'>Th</span><span style='font-size:7.0pt;font-family:"Verdana","sans-serif";color:black'>is happens when I was working for Kirk´s group and has a good aceptance between people, Maybe it will help and you don´t need to ask for blood itself.</span><span style='font-size:9.0pt;font-family:"Verdana","sans-serif";color:black'><o:p></o:p></span></p></div><div><p class=MsoNormal style='margin-bottom:12.0pt'><o:p> </o:p></p></div></div></body></html>