<html xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40">
<head>
<meta http-equiv=Content-Type content="text/html; charset=utf-8">
<meta name=Generator content="Microsoft Word 12 (filtered medium)">
<style>
<!--
/* Font Definitions */
@font-face
{font-family:Helvetica;
panose-1:2 11 6 4 2 2 2 2 2 4;}
@font-face
{font-family:"Cambria Math";
panose-1:2 4 5 3 5 4 6 3 2 4;}
@font-face
{font-family:Calibri;
panose-1:2 15 5 2 2 2 4 3 2 4;}
@font-face
{font-family:Tahoma;
panose-1:2 11 6 4 3 5 4 4 2 4;}
/* Style Definitions */
p.MsoNormal, li.MsoNormal, div.MsoNormal
{margin:0cm;
margin-bottom:.0001pt;
font-size:12.0pt;
font-family:"Times New Roman","serif";}
a:link, span.MsoHyperlink
{mso-style-priority:99;
color:blue;
text-decoration:underline;}
a:visited, span.MsoHyperlinkFollowed
{mso-style-priority:99;
color:purple;
text-decoration:underline;}
p
{mso-style-priority:99;
mso-margin-top-alt:auto;
margin-right:0cm;
mso-margin-bottom-alt:auto;
margin-left:0cm;
font-size:12.0pt;
font-family:"Times New Roman","serif";}
p.MsoAcetate, li.MsoAcetate, div.MsoAcetate
{mso-style-priority:99;
mso-style-link:"Texte de bulles Car";
margin:0cm;
margin-bottom:.0001pt;
font-size:8.0pt;
font-family:"Tahoma","sans-serif";}
span.TextedebullesCar
{mso-style-name:"Texte de bulles Car";
mso-style-priority:99;
mso-style-link:"Texte de bulles";
font-family:"Tahoma","sans-serif";}
p.msochpdefault, li.msochpdefault, div.msochpdefault
{mso-style-name:msochpdefault;
mso-margin-top-alt:auto;
margin-right:0cm;
mso-margin-bottom-alt:auto;
margin-left:0cm;
font-size:10.0pt;
font-family:"Times New Roman","serif";}
span.textedebullescar0
{mso-style-name:textedebullescar;
font-family:"Tahoma","sans-serif";}
span.emailstyle19
{mso-style-name:emailstyle19;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.emailstyle20
{mso-style-name:emailstyle20;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.emailstyle21
{mso-style-name:emailstyle21;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.EmailStyle25
{mso-style-type:personal-reply;
font-family:"Calibri","sans-serif";
color:#1F497D;}
.MsoChpDefault
{mso-style-type:export-only;
font-size:10.0pt;}
@page Section1
{size:612.0pt 792.0pt;
margin:70.85pt 70.85pt 70.85pt 70.85pt;}
div.Section1
{page:Section1;}
-->
</style>
<!--[if gte mso 9]><xml>
<o:shapedefaults v:ext="edit" spidmax="1026" />
</xml><![endif]--><!--[if gte mso 9]><xml>
<o:shapelayout v:ext="edit">
<o:idmap v:ext="edit" data="1" />
</o:shapelayout></xml><![endif]-->
</head>
<body bgcolor=white lang=FR link=blue vlink=purple style='line-height:initial'>
<div class=Section1>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Dear Crispin,<o:p></o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p> </o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>OK, I just wanted to check in this discussion what was the
current state of knowledge on the relationship between air pollution and health.<o:p></o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>See if and how misguided is the WHO, and how misguided we are,
as stovers.<o:p></o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p> </o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>It seems we still have good reasons to want to lower the
emissions of our stoves, even if we don’t know exactly how many lives we save
(or we extend, depending on how you put it).<o:p></o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>I have now enough literature, I believe, to see more or less what’s
the current state of knowledge. <o:p></o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p> </o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Regarding the last EPA news: I am all for transparency. Given
his reputation, I am not so certain about (nor confident in) what Scott Pruitt has
set out to do, but we’ll see soon enough I guess.<o:p></o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p> </o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Best,<o:p></o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><br>
Xavier<o:p></o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p> </o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p> </o:p></span></p>
<p class=MsoNormal><span style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><o:p> </o:p></span></p>
<div>
<div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0cm 0cm 0cm'>
<p class=MsoNormal><b><span style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'>De :</span></b><span
style='font-size:10.0pt;font-family:"Tahoma","sans-serif"'> Crispin
Pemberton-Pigott [mailto:crispinpigott@outlook.com] <br>
<b>Envoyé :</b> mardi 22 mai 2018 06:23<br>
<b>À :</b> Xavier Brandao; ndesai@alum.mit.edu<br>
<b>Cc :</b> 'Philip Lloyd'; 'Harold Annegarn'; 'Anil Rajvanshi';
'Discussion of biomass cooking stoves'; 'Norbert Senf'<br>
<b>Objet :</b> Re: Ultrafine particles (Re: Xavier<o:p></o:p></span></p>
</div>
</div>
<p class=MsoNormal><o:p> </o:p></p>
<div>
<p class=MsoNormal style='background:white'><span lang=EN-US style='font-family:
"Calibri","sans-serif";color:#1F497D'>Dear Xavier<o:p></o:p></span></p>
</div>
<div>
<p class=MsoNormal style='background:white'><span lang=EN-US style='font-family:
"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p>
</div>
<div>
<p class=MsoNormal style='background:white'><span lang=EN-US style='font-family:
"Calibri","sans-serif";color:#1F497D'>There is some movement related to making
the sources used to create regulations more transparent. This reflects on the
WHO's position regarding PM2.5 exposure thresholds which are rooted in EPA
regulations including the concept of 'no tolerable limit' and 'equitoxicity' of
all particles. <o:p></o:p></span></p>
</div>
<div>
<p class=MsoNormal style='background:white'><span lang=EN-US style='font-family:
"Calibri","sans-serif";color:#1F497D'><o:p> </o:p></span></p>
</div>
<p style='margin:0cm;margin-bottom:.0001pt;line-height:15.6pt;vertical-align:
baseline;outline: 0px'><span lang=EN-US style='font-size:13.0pt;font-family:
"Helvetica","sans-serif";color:#404040'>Last month EPA Administrator Scott
Pruitt requested public comment on a new rule, “<a
href="https://www.federalregister.gov/documents/2018/04/30/2018-09078/strengthening-transparency-in-regulatory-science"><span
style='font-family:"Arial","sans-serif";color:#B26600;border:none windowtext 1.0pt;
padding:0cm;text-decoration:none'>Strengthening Transparency in Regulatory
Science</span></a>” (STRS), designed to solve that problem.<o:p></o:p></span></p>
<div>
<p class=MsoNormal style='background:white'><span lang=EN-US style='font-size:
13.0pt;font-family:"Helvetica","sans-serif";color:#404040'>STRS provides that
“When promulgating significant regulatory actions, the Agency shall ensure that
dose response data and models underlying pivotal regulatory science are
publicly available in a manner sufficient for independent validation.” It
codifies what was intended in the Secret Science Reform Act of 2015, and the
Honest and Open New EPA Science Treatment Act of 2017 (HONEST Act), both of
which passed the House but never came up for vote in the Senate.</span><span
lang=EN-US style='font-family:"Calibri","sans-serif";color:#1F497D'><o:p></o:p></span></p>
</div>
<div>
<div id="_originalContent">
<div>
<p><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>This is directly relevant to your investigations. </span><span
lang=EN-US><o:p></o:p></span></p>
<p><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>regards</span><span lang=EN-US><o:p></o:p></span></p>
<p><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Crispin </span><span lang=EN-US><o:p></o:p></span></p>
<p><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><br>
<br>
</span><span lang=EN-US><o:p></o:p></span></p>
<p><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><br>
<br>
</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Dear Nikhil,</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'> </span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Sorry if I was rude in my last email, I didn’t mean to be
offensive.</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>I was just trying to say that the discussion on air pollution on
this List is sometimes confusing from my point of view. I often do not manage
to understand what you mean exactly in your posts.</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'> </span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><i><span lang=EN-US style='font-size:11.0pt;font-family:
"Calibri","sans-serif";color:#1F497D'>« </span></i><i><span lang=EN-US
style='font-size:11.0pt'>Considering that practically no data exist on low
dosages of ultrafine particles, nor is any causal pathway from such dosage to
disease incidence, toxicity claims of the type you have found are useless from
policy perspective. »</span></i><span lang=EN-US style='font-size:11.0pt'><br>
</span><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>I said « potentially », but indeed, there is not much
data about the nanoparticles toxicity:</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><a
href="https://nam01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC4689276%2F&data=02%7C01%7C%7Cbd739e9707c54484ecc108d5bf5bde22%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C636625323639372527&sdata=KxGYp%2Fh4H26DtvzOG9WDqf3E%2BvrdIJfQG%2F9SOC9GWjU%3D&reserved=0"
target="_BLANK">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4689276/</a> </span><span
lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>And, posterious to the above, the INSERM has found metal oxide
nanoparticles in lung tissue sections of welders lungs. The welders had lung
alterations. The researchers tried to confirm if the metal oxide nanoparticles
could have an effect on health. So they tested it on rats. They concluded there
is a potential risk for respiratory health:</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><a
href="https://nam01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.tandfonline.com%2Fdoi%2Fabs%2F10.1080%2F17435390.2016.1242797%3Fsrc%3Drecsys%26journalCode%3Dinan20&data=02%7C01%7C%7Cbd739e9707c54484ecc108d5bf5bde22%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C636625323639372527&sdata=TO0tsXky%2BxvlJh4FXnZoY3qdmKHPFL24I3N86ntsZ%2FU%3D&reserved=0"
target="_BLANK">https://www.tandfonline.com/doi/abs/10.1080/17435390.2016.1242797?src=recsys&journalCode=inan20</a>
</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'> </span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>So, indeed, there isn’t much evidence of nanoparticles toxicity,
and more research is needed.</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'> </span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><i><span lang=EN-US style='font-size:11.0pt'>« Whether
any premature death was from hunger or HAP exposure or contaminated alcohol,
nobody would ever know. »</span></i><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal style='margin-bottom:12.0pt'><span lang=EN-US
style='font-size:11.0pt;font-family:"Calibri","sans-serif";color:#1F497D'>Leaving
aside nanoparticles, we have no way, at all, not the slightest hint, that,
maybe, cookstoves emissions are harmful to human health? </span><span
lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'>Best,</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'><br>
Xavier</span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'> </span><span lang=EN-US><o:p></o:p></span></p>
<p class=MsoNormal><span lang=EN-US style='font-size:11.0pt;font-family:"Calibri","sans-serif";
color:#1F497D'> </span><span lang=EN-US><o:p></o:p></span></p>
<div style='border:none;border-top:solid #B5C4DF 1.0pt;padding:3.0pt 0cm 0cm 0cm'>
<p class=MsoNormal><b><span lang=EN-US style='font-size:10.0pt;font-family:
"Tahoma","sans-serif"'>De :</span></b><span lang=EN-US style='font-size:
10.0pt;font-family:"Tahoma","sans-serif"'> Nikhil Desai
[mailto:pienergy2008@gmail.com] <br>
<b>Envoyé :</b> lundi 21 mai 2018 04:22<br>
<b>À :</b> Xavier Brandao<br>
<b>Cc :</b> Philip Lloyd; Crispin Pemberton-Pigott; Harold Annegarn; Anil
Rajvanshi; Discussion of biomass cooking stoves; Norbert Senf<br>
<b>Objet :</b> Ultrafine particles (Re: Xavier</span><span lang=EN-US><o:p></o:p></span></p>
</div>
<p class=MsoNormal><span lang=EN-US> <o:p></o:p></span></p>
<div>
<div>
<div>
<p class=MsoNormal><span lang=EN-US>Xavier:<o:p></o:p></span></p>
</div>
<div>
<p class=MsoNormal><span lang=EN-US> <o:p></o:p></span></p>
</div>
<div>
<p class=MsoNormal style='margin-bottom:12.0pt'><span lang=EN-US>Rich theories
make some people rich. <br>
<br>
As with stove design and promotion, context is everything. <br>
<br>
Considering that practically no data exist on low dosages of ultrafine
particles, nor is any causal pathway from such dosage to disease incidence,
toxicity claims of the type you have found are useless from policy
perspective. <br>
<br>
Maniacal chatter is not science.<br>
<br>
Preventing exposures to ultrafine particles may or may not prevent premature
deaths. Even Kirk Smith and Ajay Pilarisetti accept as much, considering their
methodologies for aDALY computations. <br>
<br>
Say, Ebola is spread by just one virus and preventing the emergence or the
spread of the virus would prevent premature death. There is no similar
potential with ultrafine particles generally. Too many sources, varying
compositions, confounding factors.<br>
<br>
Ultrafine particle emissions are a new fad in cookstove business. Fads kill
people by omission. Whether any premature death was from hunger or HAP exposure
or contaminated alcohol, nobody would ever know. <br>
<br>
I propose the ISO process be subjected to premature death. <br>
<br>
<o:p></o:p></span></p>
</div>
<div>
<p class=MsoNormal><span lang=EN-US>Nikhil<o:p></o:p></span></p>
<div>
<p class=MsoNormal><span lang=EN-US>Skype: nikhildesai888<o:p></o:p></span></p>
</div>
</div>
<blockquote style='margin-top:5.0pt;margin-bottom:5.0pt'>
<div>
<div id="m_-3009708901836949572DAB4FAD8-2DD7-40BB-A1B8-4E2AA1F9FDF2">
<p class=MsoNormal><span lang=EN-US> <o:p></o:p></span></p>
</div>
</div>
</blockquote>
</div>
</div>
</div>
<p class=MsoNormal><span lang=EN-US><br>
<br>
<o:p></o:p></span></p>
</div>
</div>
</div>
</body>
</html>