[Stoves] CO- and Oxygen-affinity to haemoglobine

[frank]

Martin, stovers,

Great bit of info...

I was wondering if nitrates work the same as CO?  Drinking water has a 
limit of 10 ppm NO3-N because for babies it reduces the oxygen in the 
blood -they say. Perhaps converting to nitrite? For adults it does not 
seem to be a problem as a green salad has lots of nitrates.

Not to change the subject - I am finding this very interesting.

Thanks
Frank


 



Boll, Martin Dr. wrote:

> Dears,
>
>  
>
> Some CO-facts, you may know, but I think the sight on that sharpens 
> our feeling about that:
>
>  
>
> -     In smokers about 10% to 15% of haemoglobin is occupied by CO. 
> Due to that, there is a higher hematokrit  (more red blood-cells than 
> normal). (already discussed)
>
> -          If someone lives on high altitudes; this person gets 
> adapted by getting more red blood-cells (already known). If a smoker 
> (living on sea-level ) travels to higher altitude (with his higher 
> hematokrit) and he/she has serious difficulties to breathe she/he will 
> stop to smoke or smokes less. By that the CO level falls at least 
> within 24 hours, but her/his hematokrit-adaption due to CO still 
> remains, and is needed and already available for the lower O2 
> partial-pressure on high levels. -Mountaineers need some days to adapt 
> their hematokrit to higher altitude. They have to stay in a 
> high-level-camp for some days.
>
> -          I think, possibly do smokers know/feel if they smoke too 
> much in aspect of high level of CO and to low adaption of the 
> hematokrit. Certainly they have the same signs as light CO-poisoning ( 
> and it is a poisoning in realty).
>
>  
>
> -          Coal-miners work under higher CO-atmosphere condition 
> within the mine. Their body responses even with adaption to higher 
> hematokrit.
>
>  
>
> -           Mind, persons with low hematokrit are serious poisoned by 
> lower CO-concentrations, than persons with normal hematokrit.
>
>  
>
> -          During pregnancy the baby suffers from low oxygen-transport 
> due to mothers blood-CO-rising by smoking. -Fetal hemoglobin has not 
> the 250-times bigger affinity to maternal-hemoglobin as CO. If it was 
> so the hemoglobin would not allow to untie the O2 for the tissue, 
> where it is needed.
>
>  
>
> -          To decide if some concentration of CO is dangerous, there 
> are a lot of aspects which aggravate or mitigate the situation and 
> these facts can summarize or diminish the poisoning effect.  
>
>  
>
> -          Concentration in the aspired air, duration of that 
> aspiration, forced or not forced respiration ( e.g. physical work 
> forces respiration; rest lowers respiration), condition of the 
> hematokrit (adaption with high hematokrit in contrary loss of blood by 
> bleeding ) adaptation or not of the body to low hematokrit (e.g. by 
> chronical lack of haemoglobin or sudden loss of blood.
>
>  
>
> -          It is very important to be aware of such summarizing 
> effects and which those are, to get a feeling of the actual poisoning 
> effect of CO for a real person under the conditions in the 
> circumstances of that real minute. It can be at the same time 
> ignorable for one person and deadly for another.
>
>  
>
> -          By googling you will get a lot of information all about 
> that. In German there is, but I am sure in English as well. It is 
> worth to do so, to get a more realistic approach to CO and its danger. 
> At least the mind is sharpened to be aware of some unnoticed dangerous 
> small circumstances, making a big difference in poisoning effect.
>
>  
>
>  
>
> *CO-average in expired air:*
>
> * (Source: 
> http://www.nichtraucher-wiesbaden.de/informationen/messgeraete/kohlenmonoxidmegeraet.html 
> )*
>
> 1 bis 3 ppm not-smokers
> 4 bis 9 ppm passive-smokers
>
> 6 bis 20 ppm few-smoker
>
> 21 bis 100 ppm much-smoker
>
>  
>
> Reason for CO-synthesis in body:
>
> (http://www.bgbau.de/d/co_vergiftung/service/_PDF_PPS/kaefferlein1.pdf )
>
>  ( main-reason: decomposing of haemoglobin)
>
> Die wichtigste endogene Quelle (endogen heißt dabei, nicht von außen 
> in den Körper
>
> getragen, sondern im Körper selbst generiert), ist der 
> Hämoglobinabbau, d.h. wenn der rote Blutfarbstoff
>
> abgebaut wird und dabei CO im Körper entsteht.
>
>  
>
> Regards
>
> Martin
>
>  
>
>  
>
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>
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-- 
Frank Shields
Soil Control Lab
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