[Stoves] CO- and Oxygen-affinity to haemoglobine
Ronald Hongsermeier
rwhongser at web.de
Wed Oct 27 00:29:36 CDT 2010
Greetings, Anand,
I'd like to you and the group a perusal of the articles on CO in
wikipedia. I'm on my way to a reformed conference in the historic
Reformation City of Heidelberg today, so I can't do more than give a
couple of links and suggest that any of you that glean any information
that are from wikipedia in other languages (or other sources) not
included here or contribute to the development of the wikipedia articles.
http://en.wikipedia.org/wiki/Carbon_monoxide
http://de.wikipedia.org/wiki/Kohlenstoffmonoxid
"In biology, carbon monoxide is naturally produced by the action of heme
oxygenase <http://en.wikipedia.org/wiki/Heme_oxygenase> 1 and 2 on the
heme <http://en.wikipedia.org/wiki/Heme> from hemoglobin
<http://en.wikipedia.org/wiki/Hemoglobin> breakdown. This process
produces a certain amount of carboxyhemoglobin
<http://en.wikipedia.org/wiki/Carboxyhemoglobin> in normal persons, even
if they do not breathe any carbon monoxide. Following the first report
that carbon monoxide is a normal neurotransmitter in 1993,^[4]
<http://en.wikipedia.org/wiki/Carbon_monoxide#cite_note-nytimes.com-3>
as well as one of three gases that naturally modulate inflammatory
responses in the body (the other two being nitric oxide
<http://en.wikipedia.org/wiki/Nitric_oxide> and hydrogen sulfide
<http://en.wikipedia.org/wiki/Hydrogen_sulfide>), carbon monoxide has
received a great deal of clinical attention as a biological regulator.
In many tissues, all three gases are known to act as anti-inflammatories
<http://en.wikipedia.org/wiki/Anti-inflammatories>, vasodilators
<http://en.wikipedia.org/wiki/Vasodilators> and encouragers of
neovascular <http://en.wikipedia.org/wiki/Neovascular> growth.^[5]
<http://en.wikipedia.org/wiki/Carbon_monoxide#cite_note-ReferenceA-4>
Clinical trials of small amounts of carbon monoxide as a drug, are
on-going."
regards,
ron
w
h
p.s. where I'm going today is:
http://www.heidelbergerkonferenz.info/programm/
On 27.10.2010 02:12, Anand Karve wrote:
> Dear Crispin,
> does this mean that our bodies are producing CO, or does it mean that
> the measuring instrument is wrong? If our bodies are producing CO and
> if haemoglobin has a higher affinity to CO than O2, the self-generated
> CO should have poisoned all of us by now.
> Yours
> A.D.Karve
> On Wed, Oct 27, 2010 at 3:03 AM, Ronald Hongsermeier <rwhongser at web.de
> <mailto:rwhongser at web.de>> wrote:
>
> I was still confused, so I read most of the Wikipedia article and
> have some understanding now, but wouldn't think that the
> production would be constant enough to make a device calibration
> on its basis.
>
> regards,
> ron
> w
> h
>
>
> On 26.10.2010 17:34, Crispin Pemberton-Pigott wrote:
>
> Hi Ron
>
> By using a calibrated combustion analyser.
>
> We breathe out far more CO than we breathe in. Actually I
> didn't test my
> combustion efficiency. I will get a CO/CO2 ratio for myself
> sometime.
>
> Regards
> Crispin
>
>
> -----Original Message-----
>
> Sorry, Crispin, but I'm confused: how do you know what you're
> breathing out
> and whether the analyzer is registering CO or something different?
>
> regards,
> ron
> w
> h
>
>
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